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1-Acylglycerol-3-Phosphate Acyltransferase
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acyl-CoA |
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CoA |
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1-acylglycerol-3-phosphate |
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1,2-diacylglycerol-3-phosphate |
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Locus Data & Links (May need to scroll right or left to show columns)
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LPAAT3
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Endomembrane
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Heterol Exp'n.; Seq. Similarity
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2 Refs
Kim, H.U., Li, Y.B., and Huang, A.H.C. (2005). Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis. Plant Cell 17 , 1073-1089.Gale, S.E., Frolov, A., Han, X.L., Bickel, P.E., Cao, L., Bowcock, A., Schaffer, J.E., and Ory, D.S. (2006). A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation. Journal of Biological Chemistry 281 , 11082-11089.
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Pollen specifc with high expression. Seq. similarity to human AGPAT3
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Data
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LPAAT4
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Endomembrane
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Seq. Similarity
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2 Refs
Kim, H.U., Li, Y.B., and Huang, A.H.C. (2005). Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis. Plant Cell 17 , 1073-1089.Gale, S.E., Frolov, A., Han, X.L., Bickel, P.E., Cao, L., Bowcock, A., Schaffer, J.E., and Ory, D.S. (2006). A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation. Journal of Biological Chemistry 281 , 11082-11089.
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Seq. Similarity to human LPAAT2 but will not complement bacterial knockout
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Data
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LPAAT5
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Endomembrane
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Seq. Similarity
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2 Refs
Kim, H.U., Li, Y.B., and Huang, A.H.C. (2005). Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis. Plant Cell 17 , 1073-1089.Gale, S.E., Frolov, A., Han, X.L., Bickel, P.E., Cao, L., Bowcock, A., Schaffer, J.E., and Ory, D.S. (2006). A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation. Journal of Biological Chemistry 281 , 11082-11089.
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Seq. Similarity to human LPAAT2 but will not complement bacterial knockout
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Data
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LPAAT2
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Endomembrane (GFP)
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Mutant Char.; Comple. of E. coli mutant Heterol Exp'n.; Seq. Similarity
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3 Refs
Kim, H.U., Li, Y.B., and Huang, A.H.C. (2005). Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis. Plant Cell 17 , 1073-1089.Gale, S.E., Frolov, A., Han, X.L., Bickel, P.E., Cao, L., Bowcock, A., Schaffer, J.E., and Ory, D.S. (2006). A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation. Journal of Biological Chemistry 281 , 11082-11089.Maisonneuve, S., Bessoule, J.J., Lessire, R., Delseny, M., and Roscoe, T.J. (2010). Expression of Rapeseed Microsomal Lysophosphatidic Acid Acyltransferase Isozymes Enhances Seed Oil Content in Arabidopsis. Plant Physiology 152 , 670-684.
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Seq. Similarity to human AGPAT2, AGPAT3 , and Brassica napus BAT1.13
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Data
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LPAAT1
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Plastid
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Mutant Char.; Comple. of E. coli mutant; Heterol Exp'n.
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3 Refs
Tzafrir, I., Pena-Muralla, R., Dickerman, A., Berg, M., Rogers, R., Hutchens, S., Sweeney, T.C., McElver, J., Aux, G., Patton, D., and Meinke, D. (2004). Identification of genes required for embryo development in Arabidopsis. Plant Physiology 135 ,1206-1220.Kim, H.U., and Huang, A.H.C. (2004). Plastid lysophosphatidyl acyltransferase is essential for embryo development in arabidopsis. Plant Physiology 134 , 1206-1216.Yu, B., Wakao, S., Fan, J., and Benning, C. (2004). Loss of plastidic lysophosphatidic acid acyltransferase causes embryo-lethality in Arabidopsis. Plant & cell physiology 45 , 503-510.
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Data
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