Acyl Lipids: enzymes

ARABIDOPSIS
ACYL-LIPID METABOLISM

ENZYME & PROTEIN DATA

Small subunits of Serine palmitoyltransferase

Is A Subunit Of Serine Palmitoyltransferase Reaction

serine

CoA + CO₂

palmitoyl-CoA

Reaction

3-ketosphinganine

Brenda: [2.3.1.50]
IUBMB: [2.3.1.50]
ExPASy: [2.3.1.50]
ExplorEnz: [2.3.1.50]
PDB: [2.3.1.50]

Enzyme Pathways

Sphingolipid I | Sphingolipid II

Locus Data & Links (May need to scroll right or left to show columns)

Locus Id (TAIR Link)	Abbrev.	Mutant(s) (click for pop-up)	Pathway(s)	Subcelluar location	Evidence for function	Key References	Comments	Microarray Expression	Proteomics data	ESTexpression in other oilseeds
At1g06515	ssSPTa	ssSPTa	Sphingolipid I Sphingolipid II		Mutant Char.; Heterol Exp'n.; in vitro assays	1 Ref Kimberlin, A.N., Majumder, S., Han, G.S., Chen, M., Cahoon, R.E., Stone, J.M., Dunn, T.M., and Cahoon, E.B. (2013). Arabidopsis 56-Amino Acid Serine Palmitoyltransferase-Interacting Proteins Stimulate Sphingolipid Synthesis, Are Essential, and Affect Mycotoxin Sensitivity. Plant Cell 25 ,4627-4639.	essential for male gametophytes, are important for FB1 sensitivity, and limit sphingolipid synthesis in planta.
At2g30942	ssSPTb	ssSPTb	Sphingolipid I Sphingolipid II		Mutant Char.; Heterol Exp'n.; in vitro assays	2 Refs Kimberlin, A.N., Majumder, S., Han, G.S., Chen, M., Cahoon, R.E., Stone, J.M., Dunn, T.M., and Cahoon, E.B. (2013). Arabidopsis 56-Amino Acid Serine Palmitoyltransferase-Interacting Proteins Stimulate Sphingolipid Synthesis, Are Essential, and Affect Mycotoxin Sensitivity. Plant Cell 25 ,4627-4639. Smith, M.A., Dauk, M., Ramadan, H., Yang, H., Seamons, L.E., Haslam, R.P., Beaudoin, F., Ramirez-Erosa, I., and Forseille, L. (2013). Involvement of Arabidopsis ACYL-COENZYME A DESATURASE-LIKE2 (At2g31360) in the Biosynthesis of the Very-Long-Chain Monounsaturated Fatty Acid Components of Membrane Lipids. Plant Physiology 161 ,81-96.	essential for male gametophytes, are important for FB1 sensitivity, and limit sphingolipid synthesis in planta.