Acyl Lipids: enzymes

ARABIDOPSIS
ACYL-LIPID METABOLISM

ENZYME & PROTEIN DATA

Multifunctional Protein

Multifunctional Protein Overall Reaction

trans-enoyl-CoA

3-ketoacyl-CoA

Brenda: [4.2.1.17] [5.3.3.8] [5.1.2.3] [1.1.1.35]
IUBMB: [4.2.1.17] [5.3.3.8] [5.1.2.3] [1.1.1.35]
ExPASy: [4.2.1.17] [5.3.3.8] [5.1.2.3] [1.1.1.35]
ExplorEnz: [4.2.1.17] [5.3.3.8] [5.1.2.3] [1.1.1.35]
PDB: [4.2.1.17] [5.3.3.8] [5.1.2.3] [1.1.1.35]

A Domain Of The Multifunctional Protein With 3-hydroxyacyl-CoA dehydrogenase Activity

NAD⁺

NADH + H⁺

3-hydroxyacyl-CoA

3-ketoacyl-CoA

Brenda: [1.1.1.35]
IUBMB: [1.1.1.35]
ExPASy: [1.1.1.35]
ExplorEnz: [1.1.1.35]
PDB: [1.1.1.35]

A Domain Of The Multifunctional Protein With 3-hydroxybutyryl-CoA epimerase Activity

S-3-hydroxybutanoyl-CoA

R-3-hydroxybutanoyl-CoA

Brenda: [5.1.2.3]
IUBMB: [5.1.2.3]
ExPASy: [5.1.2.3]
ExplorEnz: [5.1.2.3]
PDB: [5.1.2.3]

A Domain Of The Multifunctional Protein With Dodecenoyl-CoA isomerase Activity

(3trans)-dodec-3-enoyl-CoA

(2trans)-dodec-2-enoyl-CoA

Brenda: [5.3.3.8]
IUBMB: [5.3.3.8]
ExPASy: [5.3.3.8]
ExplorEnz: [5.3.3.8]
PDB: [5.3.3.8]

A Domain Of The Multifunctional Protein With Enoyl-CoA hydratase Activity

(3S)-3-hydroxyacyl-CoA

trans-2(or 3)-enoyl-CoA
+ H₂O

Brenda: [4.2.1.17]
IUBMB: [4.2.1.17]
ExPASy: [4.2.1.17]
ExplorEnz: [4.2.1.17]
PDB: [4.2.1.17]

Enzyme Pathways

TAG Degradation

Locus Data & Links (May need to scroll right or left to show columns)

Locus Id (TAIR Link)	Abbrev.	Mutant(s) (click for pop-up)	Pathway(s)	Subcelluar location	Evidence for function	Key References	Comments	Microarray Expression	Proteomics data	ESTexpression in other oilseeds
At3g06860	MFP2	mfp2	TAG Degradation	Peroxisome	Mutant Char.	1 Ref Rylott, E.L., Eastmond, P.J., Gilday, A.D., Slocombe, S.P., Larson, T.R., Baker, A., and Graham, I.A. (2006). The Arabidopsis thaliana multifunctional protein gene (MFP2) of peroxisomal beta-oxidation is essential for seedling establishment. Plant J. 45 , 930-941.	This is the main MFP that should be linked to the prt B scheme in the b-ox figure.			Data
At4g29010	AIM1	aim1	TAG Degradation	Peroxisome	Mutant Char.	1 Ref Richmond, T.A., and Bleecker, A.B. (1999). A defect in beta-oxidation causes abnormal inflorescence development in Arabidopsis. Plant Cell 11 , 1911-1923.	Developmental Context of the Phenotype			Data

Multifunctional Protein