|
Lysophosphatidic acid acyltransferase
|
Locus Data & Links (May need to scroll right or left to show columns)
|
|
|
LPAAT
CGI-58
|
|
|
Mitochondria
|
Mutant Char.; Heterol Exp'n; Activity in vitro.
|
4 Refs
Ghosh, A.K., Chauhan, N., Rajakumari, S., Daum, G., and Rajasekharan, R. (2009). At4g24160, a soluble acyl-coenzyme A-dependent lysophosphatidic acid acyltransferase. Plant Physiol. 151 , 869-881.Zechner, R., Kienesberger, P.C., Haemmerle, G., Zimmermann, R., and Lass, A. (2009). Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. J. Lipid Res. 50 , 3-21. ReviewBeranek, A., Rechberger, G., Knauer, H., Wolinski, H., Kohlwein, S.D., and Leber, R. (2009). Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast. Journal of Biological Chemistry 284 , 11572-11578.James, C.N., Horn, P.J., Case, C.R., Gidda, S.K., Zhang, D.Y., Mullen, R.T., Dyer, J.M., Anderson, R.G.W., and Chapman, K.D. (2010). Disruption of the Arabidopsis CGI-58 homologue produces Chanarin-Dorfman-like lipid droplet accumulation in plants. Proceedings of the National Academy of Sciences of the United States of America 107 ,17833-17838.
|
Also shows lipase and phospholipase activity. Seq. Similarity to mamalian CGI-58 but contains a full lipase motif; Recombinant protein shows acyltransferase, phospho- and TAG lipase activities (weak specific activity). Arabidopsis mutant with high leaf TAG content; Resembles also yeast cardiolipin deacylase
|
|
|
Data
|
|
